Atherosclerosis is the underlying cause of most cardiovascular disease, the leading cause of death in affluent Western societies. It contributes to the progression of coronary artery disease and cerebrovascular insufficiency, which lead to i
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CETP and HDL.JPG
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1991
1991
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The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction - Nature Structural and Molecular Biology - 2007
The APOA1 gene provides instructions for making a protein called apolipoprotein A-I (apoA-I). ApoA-I is a component of high-density lipoprotein (HDL). HDL is a molecule that transports cholesterol and certain fats called phospholipids through the b
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NCBI: apo-A1 gene This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes ch
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full text Production of high density lipoprotein (HDL) requires ATP-binding cassette transporter A1 (ABCA1) to drive phospholipid (PL) from the plasma membrane into extracellular apolipoprotein A-I. Unregulated accumulation of cho
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