Frank-Starling law of the heart The stroke volume of the heart increases in response to an increase in the volume of blood in the ventricles, before contraction (the end diastolic volume), when all other factors remain constant. As a larger v
Galen of Pergamon 129 - 216
Galen claimed that the liver produced blood that was then distributed to the body in a centrifugal manner, whereas air or pneuma was absorbed from the lung into the pulmonary veins and carried by arteries to the various tissues of the body. Arterie
William Harvey 1578 - 1657 De Motu Cordis - 1628: Harvey showed for the first time that the arteries and veins circulate blood through the whole body. He showed that the heart’s beat produces a constant circulation of blood through th
Galen claimed that the liver produced blood that was then distributed to the body in a centrifugal manner, whereas air or pneuma was absorbed from the lung into the pulmonary veins and carried by arteries to the various tissues of the body. Arterie
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Claude Bernard 1813 - 1878 Milieu intérieur is the key process with which Bernard is associated. He wrote, "The stability of the internal environment [the milieu intérieur] is the condition for the free and independent life." This is the un
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Otto Frank 1865 - 1944 In his postdoctoral work (Habilitationsschrift) Frank investigated the isometric and isotonic contractile behaviour of the heart and it is this work that he is best known for. Frank's work on this topic preceded that
Ernest Starling 1866 - 1927 The physiological discovery most often associated with Starling is the Law of the Heart . Occupying two years of his life (1910–1912) his investigations examined how the heart increased its output in response to
Walter B. Cannon 1871 - 1945 The concept of milieu intérieur, or a constant interior bodily environment, was developed by the celebrated French physiologist Claude Bernard in 1865. The word ‘homeostasis’ was coined by the Harvard physiologi
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^ from USC News - 2010 ^ “Dr. Bing, who earned his medical degree in Germany but emigrated soon after Hitler rose to power, did groundbreaking research on the physiology of the heart and kidneys for more than half a century. Dr. Bing first gain
Arthur C. Guyton 1919 - 2003 Arthur Guyton presented a paradigm shift from the prevailing view at the time of how the circulation works. Before Guyton, control of cardiac output was primarily considered in terms of heart rate, stroke volume
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